| Abstract Detail
Evolutionary Developmental Biology (Evo-Devo) Prigge, Michael [1], Kadakia, Nikita [2], Estelle, Mark [3]. Functional Evolution of the Auxin Receptor Family. TIR1/AFB proteins, along with Aux/IAA proteins, mediate the transcriptional response to auxin in land plants. Three distinct clades of TIR1/AFB genes were established prior to euphyllophyte radiation, and a third duplication event resulted in four clades shared by most angiosperms. The Arabidopsis genome encodes six TIR1/AFB proteins representing three of these clades. Previous work had shown functional overlap between the more closely related TIR1, AFB2, and AFB3 genes (Dharmasiri et al., 2005; Parry et al., 2009) and between the AFB4 and AFB5 genes (Prigge et al., 2016). We have extended this analysis to the whole gene family, comparing the phenotypes of all sixty-three possible mutant combinations. This analysis revealed extensive functional overlap between even the most distantly related TIR1/AFB genes as well as examples of specialization and neofunctionalization. Furthermore, higher-order mutants affirm an essential role for auxin signaling in early sporophytic development but likely not in the gametophytes. Log in to add this item to your schedule
1 - UC San Diego, Cell & Developmental Biology, 9500 Gilman Drive, Muir Biology Building Rm 4115 (Estelle Lab), Unive, La Jolla, CA, 92093, United States 2 - UC San Diego, Cell & Developmental Biology, 9500 Gilman Drive, Muir Biology Building Rm 4115 (Estelle Lab), La Jolla, CA, 92093, USA 3 - UC San Diego, Cell & Developmental Biology, 9500 Gilman Drive, La Jolla, CA, 92093, USA
Keywords: Auxin Arabidopsis.
Presentation Type: Oral Paper Session: 20, Evolutionary Developmental Biology (Evo-Devo) I Location: 113/Mayo Civic Center Date: Tuesday, July 24th, 2018 Time: 11:45 AM Number: 20015 Abstract ID:312 Candidate for Awards:None |